senp2 SUMO specific peptidase 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: senp2provided by ZNC
Official Full Name: SUMO specific peptidase 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-060810-183
See related: Ensembl:ENSDARG00000073837 AllianceGenome:ZFIN:ZDB-GENE-060810-183
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7163520; wu:fb78c01; si:rp71-56k2.4
Summary: Predicted to enable deSUMOylase activity. Predicted to be involved in protein desumoylation. Predicted to act upstream of or within proteolysis. Predicted to be active in nucleus. Orthologous to human SENP2 (SUMO specific peptidase 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 6

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (11397546..11415635)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (11162098..11180193)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fl13g06.x1 (e-PCR)
- UniSTS:202000

fb78c01.x1 (e-PCR)
- UniSTS:191411

fb78c01.x1 (e-PCR)
- UniSTS:191412

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables cysteine-type peptidase activity	IEA Inferred from Electronic Annotation more info
enables deSUMOylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables peptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein desumoylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: sentrin-specific protease 2

Names: SUMO1/sentrin/SMT3 specific peptidase 2

XP_684283.2

EC 3.4.22.-

EC 3.4.22.68

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007117.7 Reference GRCz11 Primary Assembly

Range

11397546..11415635

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_679191.10 → XP_684283.2 sentrin-specific protease 2

UniProtKB/TrEMBL

A0A8N7UST5, E7F9K9

Related

ENSDARP00000101246.3, ENSDART00000114260.5

Conserved Domains (1) summary

cl23802
Location:370 → 595

Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain