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    fgfbp2a fibroblast growth factor binding protein 2a [ Danio rerio (zebrafish) ]

    Gene ID: 793049, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fgfbp2aprovided by ZNC
    Official Full Name
    fibroblast growth factor binding protein 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8319
    See related
    Ensembl:ENSDARG00000039964 AllianceGenome:ZFIN:ZDB-GENE-030131-8319
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fgfbp2; fb08g06; wu:fb08g06
    Summary
    Predicted to enable growth factor binding activity. Predicted to be involved in cell-cell signaling. Predicted to be located in extracellular region. Is expressed in head; liver; and pharyngeal arch 2. Orthologous to human FGFBP2 (fibroblast growth factor binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See fgfbp2a in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (46449070..46451279, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (47461991..47464182, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene Bardet-Biedl syndrome 7 Neighboring gene annexin A5a Neighboring gene prominin 1a Neighboring gene si:dkey-13a3.5 Neighboring gene transmembrane anterior posterior transformation 1a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Characterization of the Zebrafish Cell Landscape at Single-Cell Resolution. Jiang M, et al. Front Cell Dev Biol, 2021. PMID 34660600, Free PMC Article
    2. Temporal and spatial expression of fgfbp genes in zebrafish. Li Y, et al. Gene, 2018 Jun 15. PMID 29551495
    3. Expression profiling identifies Sertoli and Leydig cell genes as Fsh targets in adult zebrafish testis. Crespo D, et al. Mol Cell Endocrinol, 2016 Dec 5. PMID 27566230
    4. Genome-wide analysis of facial skeletal regionalization in zebrafish. Askary A, et al. Development, 2017 Aug 15. PMID 28705894, Free PMC Article
    5. Gene Characterization of Nocturnin Paralogues in Goldfish: Full Coding Sequences, Structure, Phylogeny and Tissue Expression. Madera D, et al. Int J Mol Sci, 2023 Dec 19. PMID 38203224, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables growth factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables growth factor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell-cell signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    fibroblast growth factor binding protein 2a
    Names
    fibroblast growth factor binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001386311.1 → NP_001373240.1  fibroblast growth factor binding protein 2a precursor

      Status: VALIDATED

      Source sequence(s)
      BX004823
      UniProtKB/TrEMBL
      A0A8M1Q161, F1R8L1
      Related
      ENSDARP00000058465.5, ENSDART00000058466.6
      Conserved Domains (1) summary
      pfam06473
      Location:6 → 213
      FGF-BP1; FGF binding protein 1 (FGF-BP1)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      46449070..46451279 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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