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    nucks1b nuclear casein kinase and cyclin-dependent kinase substrate 1b [ Danio rerio (zebrafish) ]

    Gene ID: 553506, updated on 9-Dec-2024

    Summary

    Official Symbol
    nucks1bprovided by ZNC
    Official Full Name
    nuclear casein kinase and cyclin-dependent kinase substrate 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4544
    See related
    Ensembl:ENSDARG00000012777 AllianceGenome:ZFIN:ZDB-GENE-030131-4544
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fd12f12; wu:fd12f12; zgc:165430
    Summary
    Predicted to enable double-stranded DNA binding activity and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination and interstrand cross-link repair. Predicted to act upstream of or within phosphorylation. Predicted to be active in cytoplasm. Orthologous to human NUCKS1 (nuclear casein kinase and cyclin dependent kinase substrate 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See nucks1b in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (18118535..18130248, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (18192192..18203916, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene microRNA 135c-2 Neighboring gene major facilitator superfamily domain containing 4Ab Neighboring gene uncharacterized LOC137489114 Neighboring gene chemokine-like protein TAFA-4 Neighboring gene TAFA chemokine like family member 1a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables double-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables single-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in interstrand cross-link repair IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    nuclear ubiquitous casein and cyclin-dependent kinase substrate 1b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099239.1NP_001092709.1  nuclear ubiquitous casein and cyclin-dependent kinase substrate 1b

      See identical proteins and their annotated locations for NP_001092709.1

      Status: PROVISIONAL

      Source sequence(s)
      BC146720
      UniProtKB/TrEMBL
      A6H8R5
      Related
      ENSDARP00000018018.7, ENSDART00000016976.8

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      18118535..18130248 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005162072.4XP_005162129.1  nuclear ubiquitous casein and cyclin-dependent kinase substrate 1b isoform X1

      UniProtKB/TrEMBL
      A0A8M2B988