tmem35 transmembrane protein 35 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tmem35provided by ZNC
Official Full Name: transmembrane protein 35provided by ZNC
Primary source: ZFIN:ZDB-GENE-030815-1
See related: Ensembl:ENSDARG00000052567 AllianceGenome:ZFIN:ZDB-GENE-030815-1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: Xp18; tmem35a; flj14084; wu:fc41e12; zgc:110832
Summary: Predicted to enable acetylcholine receptor regulator activity. Predicted to be involved in chaperone-mediated protein complex assembly and positive regulation of protein localization to cell surface. Predicted to be located in cytoplasmic vesicle; endoplasmic reticulum membrane; and peroxisomal membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human TMEM35A (transmembrane protein 35A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (41279520..41285392, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (40912266..40918138, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fa02f03.s1 (e-PCR)
- UniSTS:189512

fa02f04.r1 (e-PCR)
- UniSTS:189513

fc41e12.x1 (e-PCR)
- UniSTS:193782

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables acetylcholine receptor regulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in chaperone-mediated protein complex assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in chaperone-mediated protein complex assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of protein localization to cell surface	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of protein localization to cell surface	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	ISS Inferred from Sequence or Structural Similarity more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in peroxisomal membrane	IEA Inferred from Electronic Annotation more info
located_in peroxisome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: novel acetylcholine receptor chaperone

Names: transmembrane protein 35A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.