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    castor2 cytosolic arginine sensor for mTORC1 subunit 2 [ Danio rerio (zebrafish) ]

    Gene ID: 327294, updated on 9-Dec-2024

    Summary

    Official Symbol
    castor2provided by ZNC
    Official Full Name
    cytosolic arginine sensor for mTORC1 subunit 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5505
    See related
    Ensembl:ENSDARG00000018985 AllianceGenome:ZFIN:ZDB-GENE-030131-5505
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    gats; gatsl2; sb:cb509; zgc:55700; zgc:66173; wu:fc27d10; wu:fd20f09; wu:fe01c02
    Summary
    Predicted to be involved in cellular response to L-arginine and negative regulation of TORC1 signaling. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in artery; blood; notochord; and yolk syncytial layer. Orthologous to several human genes including CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See castor2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (61361815..61403813)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (60677094..60719092)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene si:ch211-209a2.2 Neighboring gene si:ch211-209a2.1 Neighboring gene small nucleolar RNA SNORA18 Neighboring gene RCC1 like Neighboring gene neutrophil cytosolic factor 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in cellular response to L-arginine IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of TORC1 signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    cytosolic arginine sensor for mTORC1 subunit 2
    Names
    GATS protein-like 2
    opposite strand transcription unit to Stag3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199780.2NP_956074.2  cytosolic arginine sensor for mTORC1 subunit 2

      See identical proteins and their annotated locations for NP_956074.2

      Status: PROVISIONAL

      Source sequence(s)
      BC045430
      UniProtKB/TrEMBL
      A0A8M1PDF2, Q7ZVS6
      Related
      ENSDARP00000005214.8, ENSDART00000009507.9
      Conserved Domains (1) summary
      pfam13840
      Location:262322
      ACT_7; ACT domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      61361815..61403813
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)