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    igbp1 immunoglobulin (CD79A) binding protein 1 [ Danio rerio (zebrafish) ]

    Gene ID: 406843, updated on 9-Dec-2024

    Summary

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    Official Symbol
    igbp1provided by ZNC
    Official Full Name
    immunoglobulin (CD79A) binding protein 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2928
    See related
    Ensembl:ENSDARG00000002184 AllianceGenome:ZFIN:ZDB-GENE-040426-2928
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fi33h08; zgc:55347; wu:fi33h08; CH73-223D24.2
    Summary
    Predicted to enable protein phosphatase 2A binding activity. Predicted to be involved in regulation of dephosphorylation. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome. Orthologous to several human genes including IGBP1 (immunoglobulin binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See igbp1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (36530874..36537975)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (35930622..35937822)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene ectodysplasin A Neighboring gene transfer RNA proline (anticodon AGG) Neighboring gene wnt 11, family member 2 Neighboring gene zgc:158432 Neighboring gene TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Activating Transcription Factor 6 Contributes to Functional Recovery After Spinal Cord Injury in Adult Zebrafish. Ji Z, et al. J Mol Neurosci, 2021 Apr. PMID 32895880
    2. Hypoxia drives transient site-specific copy gain and drug-resistant gene expression. Black JC, et al. Genes Dev, 2015 May 15. PMID 25995187, Free PMC Article
    3. Evolutionary Origin and Nomenclature of Vertebrate Wnt11-Family Genes. Postlethwait JH, et al. Zebrafish, 2019 Oct. PMID 31295059, Free PMC Article
    4. Proteomics of early zebrafish embryos. Link V, et al. BMC Dev Biol, 2006 Jan 13. PMID 16412219, Free PMC Article
    5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein phosphatase 2A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    immunoglobulin-binding protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213522.1 → NP_998687.1  immunoglobulin-binding protein 1

      See identical proteins and their annotated locations for NP_998687.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045313
      Related
      ENSDARP00000015262.6, ENSDART00000006899.8
      Conserved Domains (1) summary
      pfam04177
      Location:23 → 344
      TAP42; TAP42-like family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      36530874..36537975
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005165297.5 → XP_005165354.1  immunoglobulin-binding protein 1 isoform X1

      Conserved Domains (1) summary
      pfam04177
      Location:23 → 343
      TAP42; TAP42-like family

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394594.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      286084..293178
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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