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    hnrnpl2 heterogeneous nuclear ribonucleoprotein L2 [ Danio rerio (zebrafish) ]

    Gene ID: 573096, updated on 9-Dec-2024

    Summary

    Official Symbol
    hnrnpl2provided by ZNC
    Official Full Name
    heterogeneous nuclear ribonucleoprotein L2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2707
    See related
    Ensembl:ENSDARG00000059303 AllianceGenome:ZFIN:ZDB-GENE-040426-2707
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    hnrpl; hnrnpl; fb53f10; fp61c04; zgc:66175; wu:fb53f10; wu:fp61c04
    Summary
    Predicted to enable mRNA binding activity. Acts upstream of or within regulation of skeletal muscle fiber development. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and systemic scleroderma. Orthologous to human HNRNPL (heterogeneous nuclear ribonucleoprotein L). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See hnrnpl2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (5784207..5799183, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (5796545..5811390, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene phosphorylase kinase, gamma 1a (muscle) Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 2 Neighboring gene retinol binding protein 2a, cellular Neighboring gene bromodomain and WD repeat domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC66175, MGC174516

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of skeletal muscle fiber development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    heterogeneous nuclear ribonucleoprotein L2
    Names
    heterogeneous nuclear ribonucleoprotein L

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001423736.1NP_001410665.1  heterogeneous nuclear ribonucleoprotein L2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      BX088654
      UniProtKB/TrEMBL
      A0A8M2BHI2, A8KC22, Q7SYM9
      Related
      ENSDARP00000115723.1, ENSDART00000142334.3
    2. NM_213383.2NP_998548.2  heterogeneous nuclear ribonucleoprotein L2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      BX088654
      UniProtKB/TrEMBL
      A0A0R4IVC0, A0A8M2BGY1, Q7SYM9
      Related
      ENSDARP00000139075.1, ENSDART00000171528.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      5784207..5799183 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394932.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      87359..102335 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)