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    ublcp1 ubiquitin-like domain containing CTD phosphatase 1 [ Danio rerio (zebrafish) ]

    Gene ID: 792145, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ublcp1provided by ZNC
    Official Full Name
    ubiquitin-like domain containing CTD phosphatase 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-3
    See related
    Ensembl:ENSDARG00000044492 AllianceGenome:ZFIN:ZDB-GENE-040718-3
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb33g09; zgc:86634; wu:fb33g09
    Summary
    Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in regulation of proteasome assembly. Predicted to be active in nucleus. Orthologous to human UBLCP1 (ubiquitin like domain containing CTD phosphatase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ublcp1 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (35304974..35325541, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (35270484..35291051, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene ubiquitin domain containing 2 Neighboring gene interleukin 12B, b Neighboring gene arginyl-tRNA synthetase 1 Neighboring gene si:dkeyp-23e4.3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of Class I cytokine receptors. Liongue C, et al. BMC Evol Biol, 2007 Jul 18. PMID 17640376, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC86634, MGC173839

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoprotein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of proteasome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-like domain-containing CTD phosphatase 1
    Names
    nuclear proteasome inhibitor UBLCP1
    NP_001002319.1
    NP_001186304.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002319.2 → NP_001002319.1  ubiquitin-like domain-containing CTD phosphatase 1

      See identical proteins and their annotated locations for NP_001002319.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AL716865, AW019054, CT027760, EB795208
      UniProtKB/Swiss-Prot
      Q6DI37
      UniProtKB/TrEMBL
      A0A8M9PQM9, A8E528
      Related
      ENSDARP00000065340.5, ENSDART00000065341.7
      Conserved Domains (3) summary
      TIGR02245
      Location:117 → 311
      HAD_IIID1; HAD-superfamily subfamily IIID hydrolase, TIGR02245
      smart00213
      Location:3 → 77
      UBQ; Ubiquitin homologues
      cl00155
      Location:3 → 77
      UBQ; Ubiquitin-like proteins

    2. NM_001199375.1 → NP_001186304.1  ubiquitin-like domain-containing CTD phosphatase 1

      See identical proteins and their annotated locations for NP_001186304.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AL716865, AW019054, CT027760, DT862894, EB795208
      UniProtKB/Swiss-Prot
      Q6DI37
      UniProtKB/TrEMBL
      A0A8M9PQM9, A8E528
      Related
      ENSDARP00000130882.1, ENSDART00000162189.2
      Conserved Domains (3) summary
      TIGR02245
      Location:117 → 311
      HAD_IIID1; HAD-superfamily subfamily IIID hydrolase, TIGR02245
      smart00213
      Location:3 → 77
      UBQ; Ubiquitin homologues
      cl00155
      Location:3 → 77
      UBQ; Ubiquitin-like proteins

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      35304974..35325541 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395096.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      286839..305878 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6DI37.1 GenPept UniProtKB/Swiss-Prot:Q6DI37

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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