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    fbxl9 F-box and leucine rich repeat protein [ Danio rerio (zebrafish) ]

    Gene ID: 799466, updated on 4-Jan-2025

    Summary

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    Official Symbol
    fbxl9provided by ZNC
    Official Full Name
    F-box and leucine rich repeat proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7165
    See related
    Ensembl:ENSDARG00000076425 AllianceGenome:ZFIN:ZDB-GENE-030131-7165
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    lrrc29; fk91e06; wu:fk91e06; si:ch73-336h18.1
    Summary
    Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXL9P (F-box and leucine rich repeat protein, pseudogene). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See fbxl9 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (17478703..17494393, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (17382303..17398764, complement)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene E2F transcription factor 4 Neighboring gene engulfment and cell motility 3 Neighboring gene tripartite motif containing 35-40 Neighboring gene matrix metallopeptidase 15a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 29; F-box/LRR-repeat protein 2
    Names
    leucine rich repeat containing 29

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      17478703..17494393 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009297959.4 → XP_009296234.1  F-box/LRR-repeat protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M3AZN4
      Conserved Domains (3) summary
      cd09293
      Location:215 → 427
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:331 → 359
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:4 → 49
      F-box-like; F-box-like

    2. XM_001339783.9 → XP_001339819.4  F-box/LRR-repeat protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M1PUS3, X1WDA2
      Related
      ENSDARP00000128199.1, ENSDART00000154134.2
      Conserved Domains (3) summary
      cd09293
      Location:215 → 427
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:331 → 359
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:4 → 49
      F-box-like; F-box-like
    Nucleotide Protein Strain
    Heading Accession and Version

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