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    galnt14 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) [ Danio rerio (zebrafish) ]

    Gene ID: 562739, updated on 9-Dec-2024

    Summary

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    Official Symbol
    galnt14provided by ZNC
    Official Full Name
    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041014-351
    See related
    Ensembl:ENSDARG00000023448 AllianceGenome:ZFIN:ZDB-GENE-041014-351
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-147c1.1
    Summary
    Predicted to enable polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Orthologous to human GALNT14 (polypeptide N-acetylgalactosaminyltransferase 14). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See galnt14 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (37970412..38119912)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (38128618..38217033)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene vasohibin 2 Neighboring gene angel homolog 2 (Drosophila) Neighboring gene uncharacterized LOC101886926 Neighboring gene EH-domain containing 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    polypeptide N-acetylgalactosaminyltransferase 14
    NP_001038460.1
    XP_005160882.1
    XP_017207989.1
    XP_021324149.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044995.2 → NP_001038460.1  polypeptide N-acetylgalactosaminyltransferase 14

      See identical proteins and their annotated locations for NP_001038460.1

      Status: PROVISIONAL

      Source sequence(s)
      BX897693, CR626885
      UniProtKB/TrEMBL
      A0A8M1N9Y0, Q5RFV2
      Related
      ENSDARP00000036450.4, ENSDART00000032161.6
      Conserved Domains (4) summary
      cd02510
      Location:116 → 410
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      COG0463
      Location:111 → 395
      WcaA; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]
      cd00161
      Location:424 → 551
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00652
      Location:423 → 549
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      37970412..38119912
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017352500.3 → XP_017207989.1  polypeptide N-acetylgalactosaminyltransferase 14 isoform X3

      UniProtKB/TrEMBL
      A0A8M6Z2P3

    2. XM_021468474.2 → XP_021324149.1  polypeptide N-acetylgalactosaminyltransferase 14 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PHF5
      Conserved Domains (2) summary
      cd02510
      Location:135 → 429
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:442 → 568
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    3. XM_005160825.4 → XP_005160882.1  polypeptide N-acetylgalactosaminyltransferase 14 isoform X2

      See identical proteins and their annotated locations for XP_005160882.1

      UniProtKB/TrEMBL
      A0A8M1N9Y0, Q5RFV2
      Conserved Domains (4) summary
      cd02510
      Location:116 → 410
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      COG0463
      Location:111 → 395
      WcaA; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]
      cd00161
      Location:424 → 551
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00652
      Location:423 → 549
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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