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    si:ch73-206d17.1 si:ch73-206d17.1 [ Danio rerio (zebrafish) ]

    Gene ID: 561155, updated on 9-Dec-2024

    Summary

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    Official Symbol
    si:ch73-206d17.1provided by ZNC
    Official Full Name
    si:ch73-206d17.1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090313-143
    See related
    Ensembl:ENSDARG00000086159 AllianceGenome:ZFIN:ZDB-GENE-090313-143
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    lyn
    Summary
    Predicted to enable protein tyrosine kinase activity. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human STYK1 (serine/threonine/tyrosine kinase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See si:ch73-206d17.1 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (26491943..26498442)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (26565397..26571643)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene lysine-specific demethylase 9 Neighboring gene membrane associated guanylate kinase, WW and PDZ domain containing 3a Neighboring gene si:dkey-205h13.2 Neighboring gene transmembrane protein 269

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Conservation and early expression of zebrafish tyrosine kinases support the utility of zebrafish as a model for tyrosine kinase biology. Challa AK, et al. Zebrafish, 2013 Sep. PMID 23234507, Free PMC Article
    2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables non-membrane spanning protein tyrosine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tyrosine-protein kinase STYK1
    Names
    styk1b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      26491943..26498442
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_684560.7 → XP_689652.2  tyrosine-protein kinase STYK1 isoform X1

      UniProtKB/TrEMBL
      A0A8N7UVU0, E7FGQ0
      Related
      ENSDARP00000115394.1, ENSDART00000132905.2
      Conserved Domains (2) summary
      pfam07714
      Location:102 → 362
      Pkinase_Tyr; Protein tyrosine kinase
      cl21453
      Location:102 → 363
      PKc_like; Protein Kinases, catalytic domain

    2. XM_068216911.1 → XP_068073012.1  tyrosine-protein kinase STYK1 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

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