mad1l1 mitotic arrest deficient 1 like 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mad1l1provided by ZNC
Official Full Name: mitotic arrest deficient 1 like 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1081
See related: Ensembl:ENSDARG00000033852 AllianceGenome:ZFIN:ZDB-GENE-040426-1081
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56571
Summary: Predicted to be involved in attachment of mitotic spindle microtubules to kinetochore and mitotic spindle assembly checkpoint signaling. Predicted to be located in nucleus. Predicted to be active in kinetochore; mitotic spindle; and nuclear envelope. Human ortholog(s) of this gene implicated in lymphoma; mosaic variegated aneuploidy syndrome 7 with inflammation and tumor predisposition; and prostate cancer. Orthologous to human MAD1L1 (mitotic arrest deficient 1 like 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (9740800..9858521, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (9056689..9174410, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in attachment of mitotic spindle microtubules to kinetochore	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitotic spindle assembly checkpoint signaling	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mitotic spindle assembly checkpoint signaling	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in kinetochore	IBA Inferred from Biological aspect of Ancestor more info
is_active_in mitotic spindle	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nuclear envelope	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mitotic spindle assembly checkpoint protein MAD1

Names: MAD1 mitotic arrest deficient-like 1; mitotic arrest deficient-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.