txnipa thioredoxin interacting protein a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: txnipaprovided by ZNC
Official Full Name: thioredoxin interacting protein aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030804-10
See related: Ensembl:ENSDARG00000036107 AllianceGenome:ZFIN:ZDB-GENE-030804-10
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: txnip; sb:cb368
Summary: Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in protein transport. Predicted to be active in cytoplasm. Is expressed in several structures, including Kupffer's vesicle; cardiovascular system; endocrine system; mesoderm; and nervous system. Orthologous to human TXNIP (thioredoxin interacting protein). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 19

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (24488455..24492326)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (24904232..24908103)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ubiquitin protein ligase binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in nervous system development	IEA Inferred from Electronic Annotation more info
involved_in protein transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: thioredoxin interacting protein a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200087.1 → NP_956381.1 thioredoxin interacting protein a

See identical proteins and their annotated locations for NP_956381.1

Status: PROVISIONAL

Source sequence(s)

BC049493

UniProtKB/TrEMBL

F6P2P5, Q6NWX9, Q7ZWB6

Related

ENSDARP00000052420.3, ENSDART00000052421.4

Conserved Domains (2) summary

smart01017
Location:178 → 304

Arrestin_C; Arrestin (or S-antigen), C-terminal domain

cl22903
Location:11 → 155

Arrestin_N; Arrestin (or S-antigen), N-terminal domain