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    tut7 terminal uridylyl transferase 7 [ Danio rerio (zebrafish) ]

    Gene ID: 562358, updated on 4-Jan-2025

    Summary

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    Official Symbol
    tut7provided by ZNC
    Official Full Name
    terminal uridylyl transferase 7provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-101209-1
    See related
    AllianceGenome:ZFIN:ZDB-GENE-101209-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zcchc6
    Summary
    Enables uridylyltransferase activity. Involved in RNA 3' uridylation. Is expressed in fin; gut; head; ovary; and testis. Orthologous to human TUT7 (terminal uridylyl transferase 7). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See tut7 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (69446055..69484984, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (68674265..68713045, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene cyclin O Neighboring gene iron-sulfur cluster assembly 1 Neighboring gene phosphoserine aminotransferase 1 Neighboring gene transmembrane protein 116

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Terminal Uridylyltransferases Execute Programmed Clearance of Maternal Transcriptome in Vertebrate Embryos. Chang H, et al. Mol Cell, 2018 Apr 5. PMID 29625039
    2. Hen1 is required for oocyte development and piRNA stability in zebrafish. Kamminga LM, et al. EMBO J, 2010 Nov 3. PMID 20859253, Free PMC Article
    3. Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4). Thornton JE, et al. Nucleic Acids Res, 2014 Oct. PMID 25223788, Free PMC Article
    4. Screening by deep sequencing reveals mediators of microRNA tailing in C. elegans. Vieux KF, et al. Nucleic Acids Res, 2021 Nov 8. PMID 34586415, Free PMC Article
    5. Identification of zebrafish magnetoreceptor and cryptochrome homologs. Zhou Z, et al. Sci China Life Sci, 2016 Dec. PMID 27614751

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA uridylyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables uridylyltransferase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables uridylyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA 3' uridylation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in RNA 3' uridylation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in RNA 3' uridylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    terminal uridylyltransferase 7
    Names
    TUTase7
    zinc finger, CCHC domain containing 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      69446055..69484984 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068221378.1 → XP_068077479.1  terminal uridylyltransferase 7

      UniProtKB/TrEMBL
      A0A8M9Q3V3
    Nucleotide Protein Strain
    Heading Accession and Version

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