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    phf21aa PHD finger protein 21Aa [ Danio rerio (zebrafish) ]

    Gene ID: 497383, updated on 9-Dec-2024

    Summary

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    Official Symbol
    phf21aaprovided by ZNC
    Official Full Name
    PHD finger protein 21Aaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050208-99
    See related
    Ensembl:ENSDARG00000006878 AllianceGenome:ZFIN:ZDB-GENE-050208-99
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7138823; si:dkey-23n7.9
    Summary
    Predicted to enable chromatin binding activity. Predicted to be part of histone deacetylase complex. Is expressed in central nervous system and neural plate. Orthologous to human PHF21A (PHD finger protein 21A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See phf21aa in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (38821438..38861745, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (38550183..38590485, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene zgc:110699 Neighboring gene ATG13 autophagy related 13 homolog (S. cerevisiae) Neighboring gene harbinger transposase derived 1 Neighboring gene cAMP responsive element binding protein 3-like 1 Neighboring gene uncharacterized LOC101882371 Neighboring gene diacylglycerol kinase, zeta a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. ZebraShare: a new venue for rapid dissemination of zebrafish mutant data. DeLaurier A, et al. PeerJ, 2021. PMID 33954026, Free PMC Article
    2. Characterization of the Apelin/Elabela Receptors (APLNR) in Chickens, Turtles, and Zebrafish: Identification of a Novel Apelin-Specific Receptor in Teleosts. Zhang J, et al. Front Endocrinol (Lausanne), 2018. PMID 30631305, Free PMC Article
    3. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of histone deacetylase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    PHD finger protein 21Aa
    Names
    PHD finger protein 21A
    mutant PHD finger protein 21Aa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001328015.1 → NP_001314944.1  PHD finger protein 21Aa

      Status: VALIDATED

      Source sequence(s)
      BX957256
      UniProtKB/TrEMBL
      A0A8M1P9R5, F1RCE3
      Related
      ENSDARP00000028385.8, ENSDART00000037361.10
      Conserved Domains (1) summary
      PHA03247
      Location:75 → 374
      PHA03247; large tegument protein UL36; Provisional

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      38821438..38861745 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009303358.4 → XP_009301633.1  PHD finger protein 21Aa isoform X2

      UniProtKB/TrEMBL
      A0A1D5NSA1, A0A8M3BB60
      Related
      ENSDARP00000142711.1, ENSDART00000173953.2
      Conserved Domains (1) summary
      PHA03247
      Location:87 → 402
      PHA03247; large tegument protein UL36; Provisional

    2. XM_009303359.4 → XP_009301634.1  PHD finger protein 21Aa isoform X3

      UniProtKB/TrEMBL
      A0A8M3AUE6
      Conserved Domains (1) summary
      pfam01017
      Location:21 → 98
      STAT_alpha; STAT protein, all-alpha domain

    3. XM_009303357.4 → XP_009301632.1  PHD finger protein 21Aa isoform X1

      UniProtKB/TrEMBL
      A0A1D5NSS3, A0A8M3AUG0
      Related
      ENSDARP00000142891.1, ENSDART00000173629.2
      Conserved Domains (1) summary
      pfam01017
      Location:21 → 98
      STAT_alpha; STAT protein, all-alpha domain

    RNA

    1. XR_662173.4 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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