ssbp1 single-stranded DNA binding protein 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ssbp1provided by ZNC
Official Full Name: single-stranded DNA binding protein 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-050417-340
See related: Ensembl:ENSDARG00000039350 AllianceGenome:ZFIN:ZDB-GENE-050417-340
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: MtSSB; Mt-SSB; zgc:110325
Summary: Predicted to enable single-stranded DNA binding activity. Predicted to be involved in mitochondrial DNA replication and positive regulation of helicase activity. Predicted to act upstream of or within DNA replication. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial nucleoid. Is expressed in liver. Human ortholog(s) of this gene implicated in optic atrophy. Orthologous to human SSBP1 (single stranded DNA binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	4	NC_007115.7 (4752666..4756284, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	4	NC_007115.6 (4744096..4747714, complement)

Chromosome 4 - NC_007115.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables enzyme activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables single-stranded DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables single-stranded DNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA replication	IEA Inferred from Electronic Annotation more info
involved_in DNA unwinding involved in DNA replication	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial genome maintenance	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of mitochondrial DNA replication	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrial nucleoid	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial nucleoid	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: single-stranded DNA-binding protein, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001017806.1 → NP_001017806.1 single-stranded DNA-binding protein, mitochondrial

See identical proteins and their annotated locations for NP_001017806.1

Status: PROVISIONAL

Source sequence(s)

BC092875

UniProtKB/Swiss-Prot

B8A5I7, Q568F8

Related

ENSDARP00000057506.3, ENSDART00000057507.4

Conserved Domains (2) summary

COG0629
Location:28 → 142

Ssb; Single-stranded DNA-binding protein [Replication, recombination and repair]

cl09930
Location:26 → 140

RPA_2b-aaRSs_OBF_like; Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.