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    dixdc1b DIX domain containing 1b [ Danio rerio (zebrafish) ]

    Gene ID: 794716, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dixdc1bprovided by ZNC
    Official Full Name
    DIX domain containing 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041008-148
    See related
    Ensembl:ENSDARG00000056267 AllianceGenome:ZFIN:ZDB-GENE-041008-148
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7138279
    Summary
    Predicted to be involved in canonical Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be active in cytosol. Orthologous to human DIXDC1 (DIX domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See dixdc1b in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (25068559..25118619)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (25031937..25082014)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene junctional adhesion molecule 3b Neighboring gene zgc:171740 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 Neighboring gene si:dkey-183i3.5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Immunoglobulin superfamily receptor Junctional adhesion molecule 3 (Jam3) requirement for melanophore survival and patterning during formation of zebrafish stripes. Eom DS, et al. Dev Biol, 2021 Aug. PMID 33933422, Free PMC Article
    2. The 13q and 11q B-cell chronic lymphocytic leukaemia-associated regions derive from a common ancestral region in the zebrafish. Auer RL, et al. Br J Haematol, 2007 Jun. PMID 17488487
    3. Early depletion of primordial germ cells in zebrafish promotes testis formation. Tzung KW, et al. Stem Cell Reports, 2015 Jan 13. PMID 25434820, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dixin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      25068559..25118619
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005161265.5 → XP_005161322.1  dixin isoform X2

      UniProtKB/TrEMBL
      A0A8M1QUQ3, A0A8M2B876
      Related
      ENSDARP00000137191.2, ENSDART00000167523.2
      Conserved Domains (3) summary
      cd00014
      Location:13 → 117
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam00778
      Location:593 → 667
      DIX; DIX domain
      pfam02050
      Location:328 → 441
      FliJ; Flagellar FliJ protein

    2. XM_068216057.1 → XP_068072158.1  dixin isoform X1

      UniProtKB/TrEMBL
      A0A8M1QUQ3
      Related
      ENSDARP00000073112.4, ENSDART00000078651.5
    Nucleotide Protein Strain
    Heading Accession and Version

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