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    lrrc61 leucine rich repeat containing 61 [ Danio rerio (zebrafish) ]

    Gene ID: 553439, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lrrc61provided by ZNC
    Official Full Name
    leucine rich repeat containing 61provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060616-245
    See related
    Ensembl:ENSDARG00000077357 AllianceGenome:ZFIN:ZDB-GENE-060616-245
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:136338; si:dkey-200j6.2
    Summary
    Predicted to be involved in outer dynein arm assembly. Predicted to be active in cytoplasm. Orthologous to human LRRC61 (leucine rich repeat containing 61). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See lrrc61 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (25737374..25747464)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (25642303..25652395)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene TBC1 domain family, member 2B Neighboring gene calcium and integrin binding family member 2 Neighboring gene uncharacterized LOC103909860 Neighboring gene isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha Neighboring gene uncharacterized LOC103909861

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC136338

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in outer dynein arm assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 61

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042754.1 → NP_001036219.1  leucine-rich repeat-containing protein 61

      See identical proteins and their annotated locations for NP_001036219.1

      Status: PROVISIONAL

      Source sequence(s)
      BC117587
      UniProtKB/TrEMBL
      Q1ED18
      Related
      ENSDARP00000098514.3, ENSDART00000108476.4
      Conserved Domains (1) summary
      sd00031
      Location:54 → 81
      LRR_1; leucine-rich repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      25737374..25747464
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005163094.5 → XP_005163151.1  leucine-rich repeat-containing protein 61 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BA54
      Conserved Domains (1) summary
      sd00031
      Location:54 → 81
      LRR_1; leucine-rich repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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