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    syt9a synaptotagmin IXa [ Danio rerio (zebrafish) ]

    Gene ID: 798433, updated on 9-Dec-2024

    Summary

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    Official Symbol
    syt9aprovided by ZNC
    Official Full Name
    synaptotagmin IXaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031002-18
    See related
    Ensembl:ENSDARG00000003994 AllianceGenome:ZFIN:ZDB-GENE-031002-18
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:cb844
    Summary
    Predicted to enable SNARE binding activity; calcium ion sensor activity; and calcium-dependent phospholipid binding activity. Predicted to be involved in positive regulation of vesicle fusion; regulation of calcium ion-dependent exocytosis; and vesicle-mediated transport. Predicted to be located in membrane. Predicted to be active in dense core granule; exocytic vesicle; and plasma membrane. Is expressed in nervous system; neural tube; and trigeminal placode. Orthologous to human SYT9 (synaptotagmin 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See syt9a in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (28988354..29062039)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (29010432..29080301)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene spondin 1a Neighboring gene uncharacterized LOC137488291 Neighboring gene si:ch211-174j14.2 Neighboring gene uncharacterized LOC137488292 Neighboring gene uncharacterized LOC137488293 Neighboring gene PPFIA binding protein 2a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Expression and distribution of synaptotagmin family members in the zebrafish retina. Henry D, et al. J Comp Neurol, 2022 Mar. PMID 34468021, Free PMC Article
    2. Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans. Craxton M. BMC Genomics, 2007 Jul 31. PMID 17672888, Free PMC Article
    3. Synaptotagmin gene content of the sequenced genomes. Craxton M. BMC Genomics, 2004 Jul 6. PMID 15238157, Free PMC Article
    4. Common responses of fish embryos to metals: an integrated analysis of transcriptomes and methylomes in zebrafish embryos under the stress of copper ions or silver nanoparticles. Tai Z, et al. Metallomics, 2019 Sep 1. PMID 31468037
    5. A manual collection of Syt, Esyt, Rph3a, Rph3al, Doc2, and Dblc2 genes from 46 metazoan genomes--an open access resource for neuroscience and evolutionary biology. Craxton M. BMC Genomics, 2010 Jan 15. PMID 20078875, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion sensor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium-dependent phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of vesicle fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of calcium ion-dependent exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in dense core granule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in exocytic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    synaptotagmin-9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      28988354..29062039
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001336022.9 → XP_001336058.4  synaptotagmin-9

      UniProtKB/TrEMBL
      A0A8M1Q755, E7F1D9
      Related
      ENSDARP00000003622.7, ENSDART00000018685.9
      Conserved Domains (2) summary
      cd08403
      Location:390 → 523
      C2B_Synaptotagmin-3-5-6-9-10; C2 domain second repeat present in Synaptotagmins 3, 5, 6, 9, and 10
      cl14603
      Location:257 → 381
      C2; C2 domain
    Nucleotide Protein
    Heading Accession and Version

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