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    gpat2 glycerol-3-phosphate acyltransferase 2, mitochondrial [ Danio rerio (zebrafish) ]

    Gene ID: 558437, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gpat2provided by ZNC
    Official Full Name
    glycerol-3-phosphate acyltransferase 2, mitochondrialprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050309-118
    See related
    Ensembl:ENSDARG00000053575 AllianceGenome:ZFIN:ZDB-GENE-050309-118
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7149526; zgc:162485
    Summary
    Predicted to enable glycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in glycerophospholipid metabolic process and triglyceride biosynthetic process. Predicted to act upstream of or within cellular lipid metabolic process. Predicted to be located in membrane. Predicted to be active in mitochondrion. Orthologous to human GPAT2 (glycerol-3-phosphate acyltransferase 2, mitochondrial). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See gpat2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (41035230..41173485)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (41001258..41139397)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496303 Neighboring gene uncharacterized LOC110440018 Neighboring gene fumarylacetoacetate hydrolase domain containing 2A Neighboring gene zgc:152830

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. UPLC-TOF-MS/MS metabolomics analysis of zebrafish metabolism by spirotetramat. Zhang J, et al. Environ Pollut, 2020 Nov. PMID 32798906
    2. The Presence or Absence of Intestinal Microbiota Affects Lipid Deposition and Related Genes Expression in Zebrafish (Danio rerio). Sheng Y, et al. Front Microbiol, 2018. PMID 29896183, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycerol-3-phosphate O-acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycerol-3-phosphate O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycerophospholipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in triglyceride biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    glycerol-3-phosphate acyltransferase 2, mitochondrial
    NP_001082849.1
    XP_068079077.1
    XP_068079078.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001089380.2 → NP_001082849.1  glycerol-3-phosphate acyltransferase 2, mitochondrial

      See identical proteins and their annotated locations for NP_001082849.1

      Status: VALIDATED

      Source sequence(s)
      CT737130, CU683877, CU929223
      UniProtKB/TrEMBL
      A0A8M1ND06, A4QP00
      Related
      ENSDARP00000118422.2, ENSDART00000141349.4
      Conserved Domains (1) summary
      cl17185
      Location:180 → 373
      LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      41035230..41173485
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068222976.1 → XP_068079077.1  glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1

    2. XM_068222977.1 → XP_068079078.1  glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X2

      Related
      ENSDARP00000070102.5, ENSDART00000075620.6
    Nucleotide Protein Strain
    Heading Accession and Version

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