rabggtb Rab geranylgeranyltransferase subunit beta [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rabggtbprovided by ZNC
Official Full Name: Rab geranylgeranyltransferase subunit betaprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2116
See related: Ensembl:ENSDARG00000068587 AllianceGenome:ZFIN:ZDB-GENE-040426-2116
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fj12b07; zgc:56443; wu:fj12b07
Summary: Predicted to enable metal ion binding activity and protein prenyltransferase activity. Predicted to contribute to Rab geranylgeranyltransferase activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be part of Rab-protein geranylgeranyltransferase complex. Is expressed in female organism. Orthologous to human RABGGTB (Rab geranylgeranyltransferase subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (26463125..26469066, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (26807491..26813432, complement)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fj12b07.x1 (e-PCR)
- UniSTS:188424

fb53e01.x1 (e-PCR)
- UniSTS:203307

fd09b04.y1 (e-PCR)
- UniSTS:195061

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
contributes_to Rab geranylgeranyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables Rab geranylgeranyltransferase activity	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables prenyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein prenyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein geranylgeranylation	IEA Inferred from Electronic Annotation more info
involved_in protein geranylgeranylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Rab-protein geranylgeranyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: geranylgeranyl transferase type-2 subunit beta

Names: Rab geranylgeranyltransferase, beta subunit

NP_998277.2

EC 2.5.1.60

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213112.2 → NP_998277.2 geranylgeranyl transferase type-2 subunit beta

See identical proteins and their annotated locations for NP_998277.2

Status: PROVISIONAL

Source sequence(s)

BC097066

UniProtKB/TrEMBL

B2GQ29, F6PBQ8, Q4V946

Related

ENSDARP00000090020.4, ENSDART00000099248.6

Conserved Domains (2) summary

PLN03201
Location:14 → 326

PLN03201; RAB geranylgeranyl transferase beta-subunit; Provisional

cd02894
Location:18 → 301

GGTase-II; Geranylgeranyltransferase type II (GGTase-II)_like proteins containing the protein prenyltransferase (PTase) domain, beta subunit (alpha 6 - alpha 6 barrel fold). GGTase-IIs are a subgroup of the protein prenyltransferase family of lipid-modifying ...