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    msraa methionine sulfoxide reductase Aa [ Danio rerio (zebrafish) ]

    Gene ID: 793910, updated on 9-Dec-2024

    Summary

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    Official Symbol
    msraaprovided by ZNC
    Official Full Name
    methionine sulfoxide reductase Aaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041014-344
    See related
    Ensembl:ENSDARG00000029587 AllianceGenome:ZFIN:ZDB-GENE-041014-344
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    msra; si:dkey-221h15.1
    Summary
    Predicted to enable L-methionine-(S)-S-oxide reductase activity and peptide-methionine (S)-S-oxide reductase activity. Predicted to be involved in cellular response to oxidative stress. Predicted to be active in cytoplasm. Orthologous to human MSRA (methionine sulfoxide reductase A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See msraa in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (38910277..39046062)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (39007398..39143183)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488676 Neighboring gene microRNA 124-2 Neighboring gene regulator of calcineurin 2 Neighboring gene uncharacterized LOC108180313 Neighboring gene cytochrome P450, family 39, subfamily A, polypeptide 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Inter-species functional interactome of nuclear steroid receptors (R1). Geronikolou SA, et al. Front Biosci (Elite Ed), 2018 Jan 1. PMID 28930614
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables L-methionine-(S)-S-oxide reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide-methionine (S)-S-oxide reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptide-methionine (S)-S-oxide reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to oxidative stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial peptide methionine sulfoxide reductase
    Names
    methionine sulfoxide reductase A
    NP_001076362.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082893.2 → NP_001076362.1  mitochondrial peptide methionine sulfoxide reductase

      Status: PROVISIONAL

      Source sequence(s)
      BX511178, BX569784
      UniProtKB/TrEMBL
      A0A8M1NC54, Q5TZ05
      Related
      ENSDARP00000047361.5, ENSDART00000047362.8
      Conserved Domains (1) summary
      PRK00058
      Location:19 → 230
      PRK00058; methionine sulfoxide reductase A; Provisional

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      38910277..39046062
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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