stk35l serine/threonine kinase 35, like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: stk35lprovided by ZNC
Official Full Name: serine/threonine kinase 35, likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041212-52
See related: Ensembl:ENSDARG00000057497 AllianceGenome:ZFIN:ZDB-GENE-041212-52
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7138176; zgc:101750
Summary: Predicted to enable eukaryotic translation initiation factor 2alpha kinase activity. Predicted to be involved in regulation of translational initiation. Predicted to act upstream of or within protein phosphorylation and regulation of autophagy. Predicted to be active in cytoplasm and nucleus. Orthologous to human STK35 (serine/threonine kinase 35). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 6

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (38845697..38858998)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (38848161..38861462)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc70f12.y1 (e-PCR)
- UniSTS:194321

fk33a06.y1 (e-PCR)
- UniSTS:200832

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in negative regulation of G2/M transition of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of G2/MI transition of meiotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of autophagy	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: serine/threonine kinase 35, like

Names: serine/threonine kinase-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008627.1 → NP_001008627.1 serine/threonine kinase 35, like

See identical proteins and their annotated locations for NP_001008627.1

Status: PROVISIONAL

Source sequence(s)

BC086732

UniProtKB/TrEMBL

B2GTB7, Q5PRB1

Related

ENSDARP00000053186.5, ENSDART00000053187.6

Conserved Domains (2) summary

smart00220
Location:60 → 388

S_TKc; Serine/Threonine protein kinases, catalytic domain

cl21453
Location:59 → 392

PKc_like; Protein Kinases, catalytic domain