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    otub1b OTU deubiquitinase, ubiquitin aldehyde binding 1b [ Danio rerio (zebrafish) ]

    Gene ID: 436773, updated on 9-Dec-2024

    Summary

    Official Symbol
    otub1bprovided by ZNC
    Official Full Name
    OTU deubiquitinase, ubiquitin aldehyde binding 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-204
    See related
    Ensembl:ENSDARG00000011462 AllianceGenome:ZFIN:ZDB-GENE-040718-204
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    otub1; fa19h07; zgc:92839; wu:fa19h07
    Summary
    Predicted to enable cysteine-type deubiquitinase activity and ubiquitin binding activity. Predicted to act upstream of or within protein deubiquitination and proteolysis. Orthologous to human OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See otub1b in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (24815812..24828869, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (24544655..24557712, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene shroom family member 4 Neighboring gene si:ch211-226l4.6 Neighboring gene citrate synthase lysine methyltransferase Neighboring gene family with sequence similarity 113 Neighboring gene uncharacterized LOC101885004

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity  
    enables cysteine-type deubiquitinase activity  
    enables cysteine-type peptidase activity  
    enables hydrolase activity  
    enables peptidase activity  
    enables ubiquitin binding  

    General protein information

    Preferred Names
    ubiquitin thioesterase OTUB1b
    Names
    OTU domain, ubiquitin aldehyde binding 1
    OTU domain, ubiquitin aldehyde binding 1b
    NP_001002500.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002500.2 → NP_001002500.2  ubiquitin thioesterase OTUB1b

      Status: VALIDATED

      Source sequence(s)
      EH433266, EH460846
      UniProtKB/TrEMBL
      A0A8M1N0M6, F6P1A9
      Related
      ENSDARP00000006133.8, ENSDART00000005853.9
      Conserved Domains (1) summary
      pfam10275
      Location:35 → 266
      Peptidase_C65; Peptidase C65 Otubain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      24815812..24828869 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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