saa serum amyloid A [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: saaprovided by ZNC
Official Full Name: serum amyloid Aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040927-15
See related: Ensembl:ENSDARG00000045999 AllianceGenome:ZFIN:ZDB-GENE-040927-15
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:103580
Summary: Acts upstream of with a positive effect on neutrophil chemotaxis. Acts upstream of with a negative effect on neutrophil-mediated killing of bacterium. Acts upstream of or within with a positive effect on cell maturation. Acts upstream of or within neutrophil migration and response to bacterium. Predicted to be located in extracellular region. Predicted to be part of high-density lipoprotein particle. Is expressed in liver and male organism. Orthologous to several human genes including SAA1 (serum amyloid A1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 7

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (12950507..12956434)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (12688552..12703718)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within acute-phase response	IEA Inferred from Electronic Annotation more info
involved_in acute-phase response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within_positive_effect cell maturation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_positive_effect neutrophil chemotaxis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of neutrophil homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within neutrophil migration	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_negative_effect neutrophil-mediated killing of bacterium	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to bacterium	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
part_of high-density lipoprotein particle	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: serum amyloid A

Names: saa1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.