wdsub1 WD repeat, sterile alpha motif and U-box domain containing 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: wdsub1provided by ZNC
Official Full Name: WD repeat, sterile alpha motif and U-box domain containing 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-061110-97
See related: Ensembl:ENSDARG00000090418 AllianceGenome:ZFIN:ZDB-GENE-061110-97
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:154085
Summary: Predicted to enable ubiquitin-protein transferase activity. Predicted to act upstream of or within protein ubiquitination. Orthologous to human WDSUB1 (WD repeat, sterile alpha motif and U-box domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (12006117..12033326)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (11770758..11798468)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ubiquitin-protein transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein ubiquitination	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: WD repeat, SAM and U-box domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077769.1 → NP_001071237.1 WD repeat, SAM and U-box domain-containing protein 1

See identical proteins and their annotated locations for NP_001071237.1

Status: PROVISIONAL

Source sequence(s)

BC124806

UniProtKB/Swiss-Prot

A0AUS0

Related

ENSDARP00000106094.2, ENSDART00000128024.3

Conserved Domains (6) summary

cd09505
Location:343 → 414

SAM_WDSUB1; SAM domain of WDSUB1 proteins

smart00454
Location:344 → 409

SAM; Sterile alpha motif

COG2319
Location:50 → 371

WD40; WD40 repeat [General function prediction only]

cd00200
Location:4 → 309

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:17 → 52

7WD40; WD40 repeat [structural motif]

cl17238
Location:418 → 483

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007117.7 Reference GRCz11 Primary Assembly

Range

12006117..12033326

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017356519.3 → XP_017212008.1 WD repeat, SAM and U-box domain-containing protein 1 isoform X1

UniProtKB/Swiss-Prot

A0AUS0

Conserved Domains (6) summary

cd09505
Location:343 → 414

SAM_WDSUB1; SAM domain of WDSUB1 proteins

smart00454
Location:344 → 409

SAM; Sterile alpha motif

COG2319
Location:50 → 371

WD40; WD40 repeat [General function prediction only]

cd00200
Location:4 → 309

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:17 → 52

7WD40; WD40 repeat [structural motif]

cl17238
Location:418 → 483

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
XM_068221798.1 → XP_068077899.1 WD repeat, SAM and U-box domain-containing protein 1 isoform X2