U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    tmem108 transmembrane protein 108 [ Danio rerio (zebrafish) ]

    Gene ID: 563089, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    tmem108provided by ZNC
    Official Full Name
    transmembrane protein 108provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091204-397
    See related
    Ensembl:ENSDARG00000090230 AllianceGenome:ZFIN:ZDB-GENE-091204-397
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-149n12.2
    Summary
    Predicted to be involved in dendrite extension; postsynaptic density organization; and retrograde axonal transport. Predicted to be located in membrane. Predicted to be active in axon; endosome; and postsynaptic density. Orthologous to human TMEM108 (transmembrane protein 108). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See tmem108 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (9744201..9874688)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (9603490..9734303)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-like modifier activating enzyme 5 Neighboring gene DNA topoisomerase II binding protein 1 Neighboring gene carnitine deficiency-associated gene expressed in ventricle 3 Neighboring gene VPS41 subunit of HOPS complex

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis. Gao L, et al. PLoS Genet, 2015 Jul. PMID 26131719, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in dendrite extension IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in postsynaptic density organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in retrograde axonal transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in postsynaptic density IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    transmembrane protein 108

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      9744201..9874688
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009297307.4 → XP_009295582.1  transmembrane protein 108 isoform X2

      UniProtKB/TrEMBL
      A0A8M3AP50
      Conserved Domains (1) summary
      pfam15759
      Location:13 → 483
      TMEM108; TMEM108 family

    2. XM_005162593.5 → XP_005162650.1  transmembrane protein 108 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B9F3, E7FAE6
      Related
      ENSDARP00000110325.2, ENSDART00000129656.3
      Conserved Domains (1) summary
      pfam15759
      Location:13 → 524
      TMEM108; TMEM108 family

    3. XM_005162594.4 → XP_005162651.1  transmembrane protein 108 isoform X3

      UniProtKB/TrEMBL
      A0A8M2B9L7
      Conserved Domains (1) summary
      pfam15759
      Location:1 → 493
      TMEM108; TMEM108 family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools