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    inka1a inka box actin regulator 1a [ Danio rerio (zebrafish) ]

    Gene ID: 692272, updated on 9-Dec-2024

    Summary

    Official Symbol
    inka1aprovided by ZNC
    Official Full Name
    inka box actin regulator 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060512-186
    See related
    Ensembl:ENSDARG00000070360 AllianceGenome:ZFIN:ZDB-GENE-060512-186
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fam212aa; sb:cb528; wu:fk96h10; zgc:136369; zgc:158531
    Summary
    Predicted to enable protein kinase binding activity and protein serine/threonine kinase inhibitor activity. Acts upstream of or within cartilage condensation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including axis; digestive system; nervous system; neural crest; and presumptive structure. Orthologous to human INKA1 (inka box actin regulator 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See inka1a in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (35050262..35056607)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (34788269..34794614)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 38 member 3a Neighboring gene guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a Neighboring gene uncharacterized LOC137496719 Neighboring gene uncharacterized LOC137496720 Neighboring gene TRAF-interacting protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC158531

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase inhibitor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cartilage condensation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cartilage development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    PAK4-inhibitor inka1
    Names
    family with sequence similarity 212, member Aa
    inca1
    induced in neural crest by AP2, 1a
    induced in neural crest by AP2-alpha protein 1
    protein FAM212A
    zinca1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079988.1NP_001073457.1  PAK4-inhibitor inka1

      See identical proteins and their annotated locations for NP_001073457.1

      Status: PROVISIONAL

      Source sequence(s)
      BC129272
      UniProtKB/Swiss-Prot
      A1L1Y9, F1QR98, Q1JQ16, Q503M7
      Related
      ENSDARP00000105046.2, ENSDART00000124800.3
      Conserved Domains (1) summary
      pfam15342
      Location:163202
      FAM212; FAM212 family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      35050262..35056607
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)