zgc:86598 zgc:86598 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zgc:86598provided by ZNC
Official Full Name: zgc:86598provided by ZNC
Primary source: ZFIN:ZDB-GENE-040625-181
See related: Ensembl:ENSDARG00000014222 AllianceGenome:ZFIN:ZDB-GENE-040625-181
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ck2a1; im:6891713; si:ch211-133n4.5
Summary: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in DNA damage response and regulation of cell cycle. Predicted to act upstream of or within protein phosphorylation. Predicted to be part of protein kinase CK2 complex. Predicted to be active in cytosol and nucleus. Orthologous to several human genes including CSNK2A1 (casein kinase 2 alpha 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 19

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (3206344..3232710)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (3265370..3291812)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein phosphorylation	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: STKc_CK2_alpha domain-containing protein

Names: casein kinase 2 alpha 1

NP_001002164.1

EC 2.7.11.1

XP_005159385.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002164.1 → NP_001002164.1 STKc_CK2_alpha domain-containing protein

See identical proteins and their annotated locations for NP_001002164.1

Status: PROVISIONAL

Source sequence(s)

BC071303

UniProtKB/TrEMBL

A0A2R8Q9K8, F6NIQ6, Q6IQV0

Related

ENSDARP00000024748.9, ENSDART00000020344.10

Conserved Domains (2) summary

cd14132
Location:20 → 325

STKc_CK2_alpha; Catalytic subunit (alpha) of the Serine/Threonine Kinase, Casein Kinase 2

pfam00069
Location:39 → 324

Pkinase; Protein kinase domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007130.7 Reference GRCz11 Primary Assembly

Range

3206344..3232710

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005159328.4 → XP_005159385.1 STKc_CK2_alpha domain-containing protein isoform X1

UniProtKB/TrEMBL

A0A8M2B6B1

Conserved Domains (3) summary

cd14132
Location:20 → 325

STKc_CK2_alpha; Catalytic subunit (alpha) of the Serine/Threonine Kinase, Casein Kinase 2

pfam00069
Location:39 → 324

Pkinase; Protein kinase domain

pfam11825
Location:334 → 379

Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1