zgc:91968 zgc:91968 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zgc:91968provided by ZNC
Official Full Name: zgc:91968provided by ZNC
Primary source: ZFIN:ZDB-GENE-040704-1
See related: Ensembl:ENSDARG00000011076 AllianceGenome:ZFIN:ZDB-GENE-040704-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: mreg; wu:fk68c04
Summary: Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in melanosome localization and phagosome maturation. Predicted to act upstream of or within melanosome transport. Predicted to be located in late endosome membrane and melanosome membrane. Is expressed in melanocyte; migratory neural crest cell; neural crest; and pigment cell. Orthologous to human MREG (melanoregulin). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

See zgc:91968 in Genome Data Viewer

Location:: chromosome: 19

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (4990545..4998944)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (5073833..5082458)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables lipid binding	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in melanosome localization	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within melanosome transport	IEA Inferred from Electronic Annotation more info
involved_in phagosome maturation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in apical plasma membrane	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in late endosome membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in lysosomal membrane	IEA Inferred from Electronic Annotation more info
located_in lysosome	IEA Inferred from Electronic Annotation more info
located_in melanosome	IEA Inferred from Electronic Annotation more info
located_in melanosome membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: melanoregulin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.