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    rpl19 ribosomal protein L19 [ Danio rerio (zebrafish) ]

    Gene ID: 406489, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rpl19provided by ZNC
    Official Full Name
    ribosomal protein L19provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2290
    See related
    Ensembl:ENSDARG00000013307 AllianceGenome:ZFIN:ZDB-GENE-040426-2290
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:77733; wu:fa91e07; wu:fb12d12
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within hemopoiesis. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in endodermal cell; intestine; liver; and pancreas. Orthologous to human RPL19 (ribosomal protein L19). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rpl19 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (16229943..16232439)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (16080143..16082639)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor-like 5C Neighboring gene calcium channel, voltage-dependent, beta 1 subunit Neighboring gene branched chain keto acid dehydrogenase E1 subunit beta, like Neighboring gene ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 Neighboring gene gap junction protein gamma 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Multiple ribosomal proteins are expressed at high levels in developing zebrafish endoderm and are required for normal exocrine pancreas development. Provost E, et al. Zebrafish, 2013 Jun. PMID 23697888, Free PMC Article
    2. Assessment of hematopoietic failure due to Rpl11 deficiency in a zebrafish model of Diamond-Blackfan anemia by deep sequencing. Zhang Z, et al. BMC Genomics, 2013 Dec 17. PMID 24341334, Free PMC Article
    3. Molecular insights into 4-nitrophenol-induced hepatotoxicity in zebrafish: transcriptomic, histological and targeted gene expression analyses. Lam SH, et al. Biochim Biophys Acta, 2013 Oct. PMID 23791553
    4. A high level of liver-specific expression of oncogenic Kras(V12) drives robust liver tumorigenesis in transgenic zebrafish. Nguyen AT, et al. Dis Model Mech, 2011 Nov. PMID 21729876, Free PMC Article
    5. Many ribosomal protein mutations are associated with growth impairment and tumor predisposition in zebrafish. Lai K, et al. Dev Dyn, 2009 Jan. PMID 19097187, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within hemopoiesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    large ribosomal subunit protein eL19
    Names
    60s ribosomal protein L19
    NP_998373.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213208.1 → NP_998373.1  large ribosomal subunit protein eL19

      See identical proteins and their annotated locations for NP_998373.1

      Status: PROVISIONAL

      Source sequence(s)
      BC062844
      UniProtKB/Swiss-Prot
      Q6DRK1, Q6P5L3
      Related
      ENSDARP00000105649.2, ENSDART00000121728.3
      Conserved Domains (1) summary
      cd01417
      Location:4 → 166
      Ribosomal_L19e_E; Ribosomal protein L19e, eukaryotic. L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      16229943..16232439
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6P5L3.1 GenPept UniProtKB/Swiss-Prot:Q6P5L3

    Gene LinkOut

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