mak16 MAK16 homolog (S. cerevisiae) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mak16provided by ZNC
Official Full Name: MAK16 homolog (S. cerevisiae)provided by ZNC
Primary source: ZFIN:ZDB-GENE-020419-35
See related: Ensembl:ENSDARG00000003527 AllianceGenome:ZFIN:ZDB-GENE-020419-35
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: mak16l; fb34e01; chunp6925; wu:fb34e01
Summary: Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be located in nucleus. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Orthologous to human MAK16 (MAK16 homolog). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (45394914..45402210, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (45387035..45394331, complement)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in maturation of 5.8S rRNA	IBA Inferred from Biological aspect of Ancestor more info
involved_in maturation of LSU-rRNA	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of preribosome, large subunit precursor	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein MAK16 homolog

Names: MAK16-like protein; mak16-like homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_173239.2 → NP_775346.2 protein MAK16 homolog

Status: VALIDATED

Source sequence(s)

CD285306, CU695141, EH436367, EH462357

UniProtKB/Swiss-Prot

Q6NYD4, Q8JGS7

UniProtKB/TrEMBL

A0A8M1PBW3, F1QDC7

Related

ENSDARP00000098580.3, ENSDART00000113837.5

Conserved Domains (3) summary

COG5129
Location:2 → 297

MAK16; Nuclear protein with HMG-like acidic region [General function prediction only]

pfam01778
Location:6 → 116

Ribosomal_L28e; Ribosomal L28e protein family

pfam04874
Location:152 → 234

Mak16; Mak16 protein C-terminal region