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    ckap4 cytoskeleton associated protein 4 [ Danio rerio (zebrafish) ]

    Gene ID: 406549, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ckap4provided by ZNC
    Official Full Name
    cytoskeleton associated protein 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2417
    See related
    Ensembl:ENSDARG00000032405 AllianceGenome:ZFIN:ZDB-GENE-040426-2417
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:85975
    Summary
    Predicted to be located in cytoplasm and plasma membrane. Is expressed in several structures, including EVL; axial mesoderm; cleithrum; corneal epithelium; and periderm. Orthologous to human CKAP4 (cytoskeleton associated protein 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ckap4 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (77975221..77979432, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (76590519..76594730, complement)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor GTPase activating protein 3 Neighboring gene IKBKB interacting protein Neighboring gene telomeric repeat binding factor a Neighboring gene ras-related protein Rab-19-like Neighboring gene zgc:194336 Neighboring gene T-complex protein 1 subunit beta-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Molecular description of eye defects in the zebrafish Pax6b mutant, sunrise, reveals a Pax6b-dependent genetic network in the developing anterior chamber. Takamiya M, et al. PLoS One, 2015. PMID 25692557, Free PMC Article
    2. The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation. Hadzhiev Y, et al. Dev Cell, 2023 Jan 23. PMID 36693321, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytoskeleton-associated protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213265.1 → NP_998430.1  cytoskeleton-associated protein 4

      See identical proteins and their annotated locations for NP_998430.1

      Status: PROVISIONAL

      Source sequence(s)
      BC067728
      UniProtKB/TrEMBL
      A0A8M1PEW8, Q6NW47
      Related
      ENSDARP00000049169.4, ENSDART00000049170.5
      Conserved Domains (1) summary
      TIGR02168
      Location:87 → 384
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      77975221..77979432 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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