U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    caprin1a cell cycle associated protein 1a [ Danio rerio (zebrafish) ]

    Gene ID: 445090, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    caprin1aprovided by ZNC
    Official Full Name
    cell cycle associated protein 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040801-226
    See related
    Ensembl:ENSDARG00000009346 AllianceGenome:ZFIN:ZDB-GENE-040801-226
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    m11s1; caprin; gpiap1; zgc:92043; wu:fb49b05; wu:fc35g01
    Summary
    Enables calcium ion binding activity and identical protein binding activity. Predicted to act upstream of or within cell differentiation and negative regulation of translation. Predicted to be active in cytoplasm. Orthologous to human CAPRIN1 (cell cycle associated protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See caprin1a in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (26998225..27021266)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (26727004..26750104)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene exostosin glycosyltransferase 2 Neighboring gene ALX homeobox 4a Neighboring gene small nucleolar RNA SNORA19 Neighboring gene nucleobindin 2a Neighboring gene ribosomal protein S13

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling. Miao H, et al. J Biol Chem, 2014 Dec 5. PMID 25331957, Free PMC Article
    2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calcium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    caprin-1a
    Names
    cytoplasmic activation/proliferation-associated protein 1
    membrane component chromosome 11 surface marker 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003484.1 → NP_001003484.1  caprin-1a

      See identical proteins and their annotated locations for NP_001003484.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078410
      UniProtKB/TrEMBL
      Q6DBQ6
      Related
      ENSDARP00000091792.3, ENSDART00000101018.6
      Conserved Domains (2) summary
      COG1579
      Location:24 → 217
      COG1579; Predicted nucleic acid-binding protein, contains Zn-ribbon domain [General function prediction only]
      pfam12287
      Location:348 → 641
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      26998225..27021266
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005172274.5 → XP_005172331.1  caprin-1a isoform X1

      UniProtKB/TrEMBL
      A0A8M2BJN4, E7FDQ5
      Related
      ENSDARP00000106234.1, ENSDART00000128110.4
      Conserved Domains (2) summary
      COG1579
      Location:24 → 217
      COG1579; Predicted nucleic acid-binding protein, contains Zn-ribbon domain [General function prediction only]
      pfam12287
      Location:348 → 641
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    2. XM_005172275.5 → XP_005172332.1  caprin-1a isoform X2

      UniProtKB/TrEMBL
      A0A8M2BJI8
      Conserved Domains (2) summary
      COG1579
      Location:24 → 217
      COG1579; Predicted nucleic acid-binding protein, contains Zn-ribbon domain [General function prediction only]
      pfam12287
      Location:348 → 600
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394691.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      29530..49795
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools