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    wnt4b wingless-type MMTV integration site family, member 4b [ Danio rerio (zebrafish) ]

    Gene ID: 791993, updated on 9-Dec-2024

    Summary

    Official Symbol
    wnt4bprovided by ZNC
    Official Full Name
    wingless-type MMTV integration site family, member 4bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-000411-1
    See related
    Ensembl:ENSDARG00000040159 AllianceGenome:ZFIN:ZDB-GENE-000411-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within negative regulation of mitotic nuclear division. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in blastomere and nervous system. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See wnt4b in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (31802203..31813018)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (31846615..31857430)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase non-receptor type 6 Neighboring gene chromodomain helicase DNA binding protein 4b Neighboring gene cell division cycle 42, like Neighboring gene myeloid leukemia factor 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cytokine activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables frizzled binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cell fate commitment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within negative regulation of mitotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
     
    involved_in neuron differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of mitotic nuclear division IGI
    Inferred from Genetic Interaction
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    wingless-type MMTV integration site family, member 4b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131500.2NP_571575.2  wingless-type MMTV integration site family, member 4b

      Status: VALIDATED

      Source sequence(s)
      BX511250
      UniProtKB/TrEMBL
      Q9IAU3
      Related
      ENSDARP00000058738.5, ENSDART00000058739.5

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      31802203..31813018
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394963.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      65485..76273
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)