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    tfip11 tuftelin interacting protein 11 [ Danio rerio (zebrafish) ]

    Gene ID: 436994, updated on 4-Jan-2025

    Summary

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    Official Symbol
    tfip11provided by ZNC
    Official Full Name
    tuftelin interacting protein 11provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-479
    See related
    Ensembl:ENSDARG00000056932 AllianceGenome:ZFIN:ZDB-GENE-040718-479
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fd15a02; zgc:86644; wu:fd15a02
    Summary
    Predicted to enable nucleic acid binding activity. Predicted to be involved in spliceosomal complex disassembly. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of U2-type post-mRNA release spliceosomal complex. Orthologous to human TFIP11 (tuftelin interacting protein 11). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See tfip11 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (17848992..17866097, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (17922646..17939754, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene Rho family GTPase 1a Neighboring gene DNA primase subunit 1 Neighboring gene small nucleolar RNA SNORD59 Neighboring gene small nucleolar RNA SNORD59 Neighboring gene nascent polypeptide associated complex subunit alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants. White RJ, et al. Elife, 2022 Feb 17. PMID 35175196, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spliceosomal complex disassembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within spliceosomal complex disassembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of U2-type post-mRNA release spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    tuftelin-interacting protein 11
    Names
    STIP-1
    septin and tuftelin-interacting protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002721.1 → NP_001002721.1  tuftelin-interacting protein 11

      See identical proteins and their annotated locations for NP_001002721.1

      Status: PROVISIONAL

      Source sequence(s)
      BC075755
      UniProtKB/Swiss-Prot
      Q6DI35
      UniProtKB/TrEMBL
      A0A8M3AMR2, F1QQ02
      Related
      ENSDARP00000073961.4, ENSDART00000079506.5
      Conserved Domains (3) summary
      pfam01585
      Location:148 → 192
      G-patch; G-patch domain
      pfam07842
      Location:390 → 659
      GCFC; GC-rich sequence DNA-binding factor-like protein
      pfam12457
      Location:23 → 103
      TIP_N; Tuftelin interacting protein N terminal

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      17848992..17866097 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6DI35.1 GenPept UniProtKB/Swiss-Prot:Q6DI35

    Gene LinkOut

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