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    clptm1l CLPTM1 like [ Danio rerio (zebrafish) ]

    Gene ID: 436653, updated on 9-Dec-2024

    Summary

    Official Symbol
    clptm1lprovided by ZNC
    Official Full Name
    CLPTM1 likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-75
    See related
    Ensembl:ENSDARG00000021048 AllianceGenome:ZFIN:ZDB-GENE-040718-75
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    CRR9p; zgc:92063
    Summary
    Predicted to enable phospholipid scramblase activity. Predicted to act upstream of or within apoptotic process and lipid transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endomembrane system and membrane. Human ortholog(s) of this gene implicated in carcinoma (multiple) and lung disease (multiple). Orthologous to human CLPTM1L (CLPTM1 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See clptm1l in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (1856250..1871185, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (1906395..1921330, complement)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene protein tyrosine kinase 2aa Neighboring gene si:ch211-149a19.3 Neighboring gene ribosomal protein lateral stalk subunit P1 Neighboring gene small nuclear ribonucleoprotein D1 polypeptide Neighboring gene gamma-glutamylcyclotransferase a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables phospholipid scramblase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lipid transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    lipid scramblase CLPTM1L
    Names
    CLPTM1-like protein
    cisplatin resistance-related protein 9
    cleft lip and palate associated transmembrane protein 1, like
    cleft lip and palate transmembrane protein 1-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002380.1NP_001002380.1  lipid scramblase CLPTM1L

      See identical proteins and their annotated locations for NP_001002380.1

      Status: PROVISIONAL

      Source sequence(s)
      BC075876
      UniProtKB/Swiss-Prot
      Q6DHU1
      Related
      ENSDARP00000008246.6, ENSDART00000004585.7
      Conserved Domains (1) summary
      pfam05602
      Location:11421
      CLPTM1; Cleft lip and palate transmembrane protein 1 (CLPTM1)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      1856250..1871185 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)