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    ttc7b tetratricopeptide repeat domain 7B [ Danio rerio (zebrafish) ]

    Gene ID: 568039, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ttc7bprovided by ZNC
    Official Full Name
    tetratricopeptide repeat domain 7Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070105-3
    See related
    Ensembl:ENSDARG00000061207 AllianceGenome:ZFIN:ZDB-GENE-070105-3
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fj46e11; zgc:153460
    Summary
    Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Predicted to be active in plasma membrane. Orthologous to human TTC7B (tetratricopeptide repeat domain 7B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ttc7b in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (26611992..26690817)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (26593566..26672424)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488104 Neighboring gene mitochondrial ribosomal protein L57 Neighboring gene calmodulin 1a Neighboring gene NRDE-2, necessary for RNA interference, domain containing

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses. Emmerich K, et al. PLoS Genet, 2023 Oct. PMID 37819938, Free PMC Article
    2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    tetratricopeptide repeat protein 7B
    Names
    tetratricopeptide repeat protein 7B-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080603.1 → NP_001074072.1  tetratricopeptide repeat protein 7B

      See identical proteins and their annotated locations for NP_001074072.1

      Status: PROVISIONAL

      Source sequence(s)
      BC127391
      UniProtKB/TrEMBL
      A1L101
      Related
      ENSDARP00000081457.4, ENSDART00000087023.6
      Conserved Domains (2) summary
      sd00006
      Location:731 → 759
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:697 → 762
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      26611992..26690817
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009293100.4 → XP_009291375.1  tetratricopeptide repeat protein 7B isoform X1

      UniProtKB/TrEMBL
      A0A8M3AJW5
      Conserved Domains (3) summary
      sd00006
      Location:803 → 831
      TPR; TPR repeat [structural motif]
      pfam07719
      Location:805 → 836
      TPR_2; Tetratricopeptide repeat
      pfam13414
      Location:805 → 867
      TPR_11; TPR repeat

    2. XM_021467208.2 → XP_021322883.1  tetratricopeptide repeat protein 7B isoform X2

      UniProtKB/TrEMBL
      A0A8M9P904
      Conserved Domains (4) summary
      sd00006
      Location:786 → 814
      TPR; TPR repeat [structural motif]
      cl26002
      Location:752 → 883
      TPR_11; TPR repeat
      cl26178
      Location:411 → 848
      pgaA; outer membrane protein PgaA; Provisional
      cl28098
      Location:373 → 431
      Tam; Trans-aconitate methyltransferase [Energy production and conversion]

    3. XM_005158520.5 → XP_005158577.1  tetratricopeptide repeat protein 7B isoform X3

      UniProtKB/TrEMBL
      A0A8M2B4X5
      Conserved Domains (3) summary
      sd00006
      Location:748 → 776
      TPR; TPR repeat [structural motif]
      pfam07719
      Location:750 → 781
      TPR_2; Tetratricopeptide repeat
      pfam13414
      Location:750 → 812
      TPR_11; TPR repeat
    Nucleotide Protein Strain
    Heading Accession and Version

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