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    crtac1a cartilage acidic protein 1a [ Danio rerio (zebrafish) ]

    Gene ID: 559626, updated on 9-Dec-2024

    Summary

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    Official Symbol
    crtac1aprovided by ZNC
    Official Full Name
    cartilage acidic protein 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-9704
    See related
    Ensembl:ENSDARG00000059826 AllianceGenome:ZFIN:ZDB-GENE-030131-9704
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ASPIP; cb184; crtac1; sb:cb184; zgc:165343
    Summary
    Predicted to be involved in axonal fasciculation. Is expressed in floor plate. Orthologous to human CRTAC1 (cartilage acidic protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See crtac1a in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (54933805..54947601, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (54256936..54269969, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene zinc finger, FYVE domain containing 27 Neighboring gene golgin A7 family, member Ba Neighboring gene R3H domain and coiled-coil containing 1-like Neighboring gene KH-type splicing regulatory protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. CRTAC1 homolog proteins are conserved from cyanobacteria to man and secreted by the teleost fish pituitary gland. Redruello B, et al. Gene, 2010 May 15. PMID 20171266
    2. Cartilage Acidic Protein a Novel Therapeutic Factor to Improve Skin Damage Repair? Félix RC, et al. Mar Drugs, 2021 Sep 25. PMID 34677440, Free PMC Article
    3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    cartilage acidic protein 1a
    Names
    cartilage acidic protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080178.1 → NP_001073647.1  cartilage acidic protein 1a precursor

      See identical proteins and their annotated locations for NP_001073647.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ351708
      UniProtKB/TrEMBL
      A0A8M1NBG8, A1XF92, E7EYQ8
      Related
      ENSDARP00000111754.2, ENSDART00000129710.4
      Conserved Domains (2) summary
      pfam07593
      Location:445 → 496
      UnbV_ASPIC; ASPIC and UnbV
      pfam13517
      Location:287 → 348
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      54933805..54947601 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021475062.2 → XP_021330737.1  cartilage acidic protein 1a isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q5Y3
      Conserved Domains (2) summary
      pfam07593
      Location:445 → 496
      UnbV_ASPIC; ASPIC and UnbV
      pfam13517
      Location:287 → 348
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

    2. XM_021475056.2 → XP_021330731.1  cartilage acidic protein 1a isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q5Y3
      Conserved Domains (2) summary
      pfam07593
      Location:445 → 496
      UnbV_ASPIC; ASPIC and UnbV
      pfam13517
      Location:287 → 348
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

    3. XM_021475068.2 → XP_021330743.1  cartilage acidic protein 1a isoform X2

      UniProtKB/TrEMBL
      A0A8M9PUJ9
      Conserved Domains (2) summary
      pfam07593
      Location:445 → 496
      UnbV_ASPIC; ASPIC and UnbV
      pfam13517
      Location:287 → 348
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

    4. XM_005160175.5 → XP_005160232.1  cartilage acidic protein 1a isoform X3

      See identical proteins and their annotated locations for XP_005160232.1

      UniProtKB/TrEMBL
      A0A8M2B710
      Conserved Domains (2) summary
      pfam07593
      Location:445 → 496
      UnbV_ASPIC; ASPIC and UnbV
      pfam13517
      Location:287 → 348
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
    Nucleotide Protein Strain
    Heading Accession and Version

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