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    grpel1 GrpE-like 1, mitochondrial [ Danio rerio (zebrafish) ]

    Gene ID: 559037, updated on 9-Dec-2024

    Summary

    Official Symbol
    grpel1provided by ZNC
    Official Full Name
    GrpE-like 1, mitochondrialprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-051120-111
    See related
    Ensembl:ENSDARG00000010021 AllianceGenome:ZFIN:ZDB-GENE-051120-111
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:123352
    Summary
    Predicted to enable adenyl-nucleotide exchange factor activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to act upstream of or within protein folding. Predicted to be located in mitochondrion. Predicted to be part of PAM complex, Tim23 associated import motor. Orthologous to human GRPEL1 (GrpE like 1, mitochondrial). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See grpel1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (39744244..39751540, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (39473227..39480512, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene si:dkey-58i8.5 Neighboring gene serine/threonine-protein kinase pim-3-like Neighboring gene cilia and flagella associated protein 184 Neighboring gene transcriptional adaptor 2B Neighboring gene sortilin-related VPS10 domain containing receptor 2 Neighboring gene sharpin and rbck1 related Neighboring gene MAF1 homolog, negative regulator of RNA polymerase III b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC123352

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables adenyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables adenyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-folding chaperone binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein import into mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of PAM complex, Tim23 associated import motor IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    grpE protein homolog 1, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037384.2NP_001032461.1  grpE protein homolog 1, mitochondrial

      See identical proteins and their annotated locations for NP_001032461.1

      Status: VALIDATED

      Source sequence(s)
      BX908792
      UniProtKB/TrEMBL
      A0A8M1N842, Q32PS5
      Related
      ENSDARP00000026495.5, ENSDART00000016803.6
      Conserved Domains (1) summary
      cd00446
      Location:72213
      GrpE; nucleotide exchange factor GrpE

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      39744244..39751540 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)