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    nubp2 nucleotide binding protein 2 (MinD homolog, E. coli) [ Danio rerio (zebrafish) ]

    Gene ID: 641290, updated on 4-Jan-2025

    Summary

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    Official Symbol
    nubp2provided by ZNC
    Official Full Name
    nucleotide binding protein 2 (MinD homolog, E. coli)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-051023-10
    See related
    Ensembl:ENSDARG00000055653 AllianceGenome:ZFIN:ZDB-GENE-051023-10
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:123336
    Summary
    Predicted to enable iron-sulfur cluster binding activity. Predicted to be involved in iron-sulfur cluster assembly. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to human NUBP2 (NUBP iron-sulfur cluster assembly factor 2, cytosolic). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See nubp2 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (39178360..39186185, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (39286373..39294198, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene TBC1 domain family, member 24 Neighboring gene ATPase H+ transporting V0 subunit cb Neighboring gene splA/ryanodine receptor domain and SOCS box containing 3b Neighboring gene uncharacterized LOC110438367

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC123336

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent FeS chaperone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron-sulfur cluster binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in iron-sulfur cluster assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cytosolic Fe-S cluster assembly factor nubp2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037114.2 → NP_001032191.2  cytosolic Fe-S cluster assembly factor nubp2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      EH446733, EH482962, EH542357
      UniProtKB/Swiss-Prot
      Q3B7Q7
      UniProtKB/TrEMBL
      A0A8M1N7W1, F1REW2
      Related
      ENSDARP00000112190.1, ENSDART00000123019.3
      Conserved Domains (2) summary
      TIGR01969
      Location:15 → 263
      minD_arch; cell division ATPase MinD, archaeal
      pfam10609
      Location:11 → 264
      ParA; NUBPL iron-transfer P-loop NTPase

    2. NM_001312901.1 → NP_001299830.1  cytosolic Fe-S cluster assembly factor nubp2 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      CU929145
      UniProtKB/Swiss-Prot
      Q3B7Q7
      UniProtKB/TrEMBL
      A0A2R8Q6P8, A0A8M1P811
      Related
      ENSDARP00000148775.1, ENSDART00000191114.1
      Conserved Domains (2) summary
      COG0489
      Location:4 → 190
      Mrp; Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster [Cell cycle control, cell division, chromosome partitioning]
      pfam10609
      Location:2 → 223
      ParA; NUBPL iron-transfer P-loop NTPase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      39178360..39186185 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3B7Q7.1 GenPept UniProtKB/Swiss-Prot:Q3B7Q7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.