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    nrip1b nuclear receptor interacting protein 1b [ Danio rerio (zebrafish) ]

    Gene ID: 100001853, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nrip1bprovided by ZNC
    Official Full Name
    nuclear receptor interacting protein 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4173
    See related
    Ensembl:ENSDARG00000068894 AllianceGenome:ZFIN:ZDB-GENE-030131-4173
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc76h12; wu:fc76h12
    Summary
    Predicted to enable signaling receptor binding activity and transcription coregulator activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including hypochord; immature eye; mesoderm; nervous system; and pectoral fin bud. Human ortholog(s) of this gene implicated in CAKUT and osteoporosis. Orthologous to human NRIP1 (nuclear receptor interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See nrip1b in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (38256650..38316157, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (38315347..38372409, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene microRNA 99-2 Neighboring gene ubiquitin specific peptidase 25 Neighboring gene SAM domain, SH3 domain and nuclear localisation signals 1b Neighboring gene glycerophosphodiester phosphodiesterase domain containing 5a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism. Feng L, et al. Dev Biol, 2010 Feb 1. PMID 19874812, Free PMC Article
    2. Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression. Bertrand S, et al. PLoS Genet, 2007 Nov. PMID 17997606, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    nuclear receptor-interacting protein 1
    Names
    RIP140-B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      38256650..38316157 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005169195.5 → XP_005169252.1  nuclear receptor-interacting protein 1

      UniProtKB/TrEMBL
      A0A8M2BGF6, F1QVR4, F8W2C1
      Related
      ENSDARP00000124782.1, ENSDART00000149580.2
      Conserved Domains (2) summary
      pfam15687
      Location:27 → 325
      NRIP1_repr_1; Nuclear receptor-interacting protein 1 repression 1
      pfam15688
      Location:402 → 702
      NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2

    2. XM_021479444.2 → XP_021335119.1  nuclear receptor-interacting protein 1

      UniProtKB/TrEMBL
      A0A8M2BGF6, F1QVR4, F8W2C1
      Conserved Domains (2) summary
      pfam15687
      Location:27 → 325
      NRIP1_repr_1; Nuclear receptor-interacting protein 1 repression 1
      pfam15688
      Location:402 → 702
      NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
    Nucleotide Protein Strain
    Heading Accession and Version

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