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    anapc5 anaphase promoting complex subunit 5 [ Danio rerio (zebrafish) ]

    Gene ID: 322854, updated on 9-Dec-2024

    Summary

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    Official Symbol
    anapc5provided by ZNC
    Official Full Name
    anaphase promoting complex subunit 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-1574
    See related
    Ensembl:ENSDARG00000008461 AllianceGenome:ZFIN:ZDB-GENE-030131-1574
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55800; wu:fb75a09
    Summary
    Predicted to be involved in anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein K11-linked ubiquitination. Predicted to act upstream of or within cell division. Predicted to be located in cytoplasm; nucleus; and spindle. Predicted to be part of anaphase-promoting complex. Orthologous to human ANAPC5 (anaphase promoting complex subunit 5). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    human mouse all
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    Genomic context

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    See anapc5 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (40186511..40205078, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (40152737..40171304, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 75Ba Neighboring gene uncharacterized LOC137496378 Neighboring gene glutathione peroxidase 8 (putative) Neighboring gene ring finger protein 34a Neighboring gene lysine (K)-specific demethylase 2Ba

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Transcriptional and histological alterations in gonad of adult zebrafish after exposure to the synthetic progestin norgestrel. Shi WJ, et al. Environ Toxicol Chem, 2017 Dec. PMID 28631837
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    anaphase-promoting complex subunit 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199622.2 → NP_955916.2  anaphase-promoting complex subunit 5

      Status: VALIDATED

      Source sequence(s)
      CABZ01073597, CABZ01073598, EH552132
      UniProtKB/TrEMBL
      A0A8M1PFK7
      Related
      ENSDARP00000132075.1, ENSDART00000158927.3
      Conserved Domains (3) summary
      sd00016
      Location:253 → 287
      Apc5; TPR repeat [structural motif]
      pfam12862
      Location:259 → 359
      ANAPC5; Anaphase-promoting complex subunit 5
      cd16270
      Location:32 → 161
      Apc5_N; N-terminal domain of the anaphase-promoting complex subunit Apc5 (or Anapc5)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      40186511..40205078 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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