coq3 coenzyme Q3 methyltransferase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: coq3provided by ZNC
Official Full Name: coenzyme Q3 methyltransferaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-364
See related: Ensembl:ENSDARG00000069857 AllianceGenome:ZFIN:ZDB-GENE-040718-364
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb14b06; fl80g11; zgc:92256; wu:fb14b06; wu:fl80g11
Summary: Predicted to enable 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity and 3-demethylubiquinol-n 3-O-methyltransferase activity. Predicted to be involved in ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate. Predicted to act upstream of or within methylation. Predicted to be located in mitochondrial inner membrane. Predicted to be extrinsic component of mitochondrial inner membrane. Predicted to be active in mitochondrion. Orthologous to human COQ3 (coenzyme Q3, methyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (32652350..32662947, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (32698320..32708917, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb24d01 (e-PCR)
- UniSTS:188988

fb24d01.x1 (e-PCR)
- UniSTS:203084

fb14b06.x1 (e-PCR)
- UniSTS:202916

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables 3-demethylubiquinol-n 3-O-methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 3-demethylubiquinol-n 3-O-methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ubiquinone biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in ubiquinone biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in extrinsic component of mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ubiquinone biosynthesis O-methyltransferase, mitochondrial

Names: coenzyme Q3 homolog, methyltransferase

NP_001002620.1

EC 2.1.1.114

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002620.2 → NP_001002620.1 ubiquinone biosynthesis O-methyltransferase, mitochondrial

See identical proteins and their annotated locations for NP_001002620.1

Status: PROVISIONAL

Source sequence(s)

BC096999

UniProtKB/TrEMBL

Q6DHK4

Related

ENSDARP00000031743.7, ENSDART00000034109.8

Conserved Domains (2) summary

TIGR01983
Location:73 → 303

UbiG; ubiquinone biosynthesis O-methyltransferase

pfam13489
Location:110 → 280

Methyltransf_23; Methyltransferase domain