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    seta SET nuclear proto-oncogene a [ Danio rerio (zebrafish) ]

    Gene ID: 323501, updated on 9-Dec-2024

    Summary

    Official Symbol
    setaprovided by ZNC
    Official Full Name
    SET nuclear proto-oncogene aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-2221
    See related
    Ensembl:ENSDARG00000031495 AllianceGenome:ZFIN:ZDB-GENE-030131-2221
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb99h10; ik:tdsubc_2c6; xx:tdsubc_2c6
    Summary
    Predicted to enable chromatin binding activity and histone binding activity. Predicted to act upstream of or within nucleosome assembly. Predicted to be located in chromatin. Predicted to be active in nucleus. Is expressed in central nervous system; optic cup; otic vesicle; and sensory system. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human SET (SET nuclear proto-oncogene). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See seta in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (2585406..2591654, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (2526863..2533111, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene GLE1 RNA export mediator Neighboring gene si:ch211-51h9.7 Neighboring gene zinc finger DHHC-type palmitoyltransferase 12a Neighboring gene solute carrier family 25 member 25a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within nucleosome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    SET nuclear proto-oncogene a
    Names
    SET translocation (myeloid leukemia-associated) A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201475.1NP_958883.1  SET nuclear proto-oncogene a

      See identical proteins and their annotated locations for NP_958883.1

      Status: PROVISIONAL

      Source sequence(s)
      BC046082
      UniProtKB/TrEMBL
      A0A8M1PCI5, Q7ZUY0
      Related
      ENSDARP00000049108.5, ENSDART00000049109.6
      Conserved Domains (1) summary
      pfam00956
      Location:37221
      NAP; Nucleosome assembly protein (NAP)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      2585406..2591654 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)