U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mtnr1bb melatonin receptor 1Bb [ Danio rerio (zebrafish) ]

    Gene ID: 30668, updated on 9-Dec-2024

    Summary

    Official Symbol
    mtnr1bbprovided by ZNC
    Official Full Name
    melatonin receptor 1Bbprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-990415-156
    See related
    Ensembl:ENSDARG00000086493 AllianceGenome:ZFIN:ZDB-GENE-990415-156
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mel1br; Mel1b-1; mel-1B-R; mtnr1br-2; mel-1B-R-B
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within rhythmic process and signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in caudal tuberal nucleus; dorsal caudal thalamic nucleus; periventricular grey zone; periventricular nucleus; and periventricular nucleus of caudal tuberculum. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MTNR1B (melatonin receptor 1B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See mtnr1bb in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (25035459..25069155, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (25066007..25099703, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496589 Neighboring gene CD209 molecule Neighboring gene protocadherin Fat 3 Neighboring gene cysteine and histidine-rich domain (CHORD) containing 1b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables melatonin receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within rhythmic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    melatonin receptor type 1B-B
    Names
    mel1b receptor B
    melatonin receptor 1B b
    melatonin receptor Mel1b Z2.6-4
    melatonin receptor type 1B z2.6
    zMel1b-1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131394.1NP_571469.1  melatonin receptor type 1B-B

      See identical proteins and their annotated locations for NP_571469.1

      Status: PROVISIONAL

      Source sequence(s)
      BX897671
      UniProtKB/Swiss-Prot
      P51049, Q5RGH4, Q804I8
      Related
      ENSDARP00000072688.2, ENSDART00000078226.4
      Conserved Domains (2) summary
      pfam00001
      Location:48299
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:39241
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      25035459..25069155 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)