U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    crygm4 crystallin, gamma M4 [ Danio rerio (zebrafish) ]

    Gene ID: 338225, updated on 9-Dec-2024

    Summary

    Official Symbol
    crygm4provided by ZNC
    Official Full Name
    crystallin, gamma M4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-120312-2
    See related
    Ensembl:ENSDARG00000008219 AllianceGenome:ZFIN:ZDB-GENE-120312-2
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Is expressed in lens. Human ortholog(s) of this gene implicated in cataract 39 multiple types. Orthologous to human CRYGB (crystallin gamma B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See crygm4 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (72028..73053)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (53986..54998)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene methyl-CpG binding domain protein 5 Neighboring gene sosondowah ankyrin repeat domain family Cb Neighboring gene transcription activator BRG1 Neighboring gene low density lipoprotein receptor b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables structural constituent of eye lens IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in lens development in camera-type eye IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in visual perception IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    crystallin, gamma M4
    Names
    gammaM4-crystallin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007791.2NP_001007792.1  crystallin, gamma M4

      See identical proteins and their annotated locations for NP_001007792.1

      Status: VALIDATED

      Source sequence(s)
      CABZ01085591
      UniProtKB/TrEMBL
      A4FVH3, Q5XTN5
      Related
      ENSDARP00000111811.1, ENSDART00000122957.2
      Conserved Domains (1) summary
      pfam00030
      Location:89169
      Crystall; Beta/Gamma crystallin

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      72028..73053
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)