dynlt2b dynein light chain Tctex-type 2B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dynlt2bprovided by ZNC
Official Full Name: dynein light chain Tctex-type 2Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-081104-219
See related: Ensembl:ENSDARG00000054255 AllianceGenome:ZFIN:ZDB-GENE-081104-219
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: tctex1d2; si:ch211-276k2.4
Summary: Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in intraciliary retrograde transport. Predicted to be located in dynein axonemal particle. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in cytoplasm. Used to study ciliopathy. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy. Orthologous to human DYNLT2B (dynein light chain Tctex-type 2B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 22

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (35472545..35478657)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (35496903..35503032)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables dynein intermediate chain binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in intraciliary retrograde transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in microtubule-based movement	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of cytoplasmic dynein complex	IBA Inferred from Biological aspect of Ancestor more info
part_of cytoplasmic dynein complex	ISS Inferred from Sequence or Structural Similarity more info
located_in dynein axonemal particle	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dynein light chain Tctex-type protein 2B

Names: Tctex1 domain containing 2; tctex1 domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.