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    rad54l2 RAD54 like 2 [ Danio rerio (zebrafish) ]

    Gene ID: 558947, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rad54l2provided by ZNC
    Official Full Name
    RAD54 like 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3097
    See related
    Ensembl:ENSDARG00000063031 AllianceGenome:ZFIN:ZDB-GENE-030131-3097
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc27a09; wu:fc27a09; si:dkey-42i9.10
    Summary
    Predicted to enable ATP-dependent chromatin remodeler activity and transcription coregulator activity. Predicted to be involved in chromatin organization. Predicted to be active in nucleus. Orthologous to human RAD54L2 (RAD54 like 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rad54l2 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (10607041..10639026)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (10577208..10609367)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene shisa family member 10, tandem duplicate 4 Neighboring gene BRCA1 associated deubiquitinase 1 Neighboring gene cytochrome b561 family, member D2 Neighboring gene Ras association domain family member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent chromatin remodeler activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    helicase ARIP4
    XP_005174062.1
    XP_005174063.1
    XP_687332.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      10607041..10639026
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_682240.10 → XP_687332.3  helicase ARIP4 isoform X2

      See identical proteins and their annotated locations for XP_687332.3

      UniProtKB/TrEMBL
      A0A8N7TAQ7, F1QKJ5, F1R3L6
      Related
      ENSDARP00000121746.2, ENSDART00000147975.3
      Conserved Domains (3) summary
      cd00046
      Location:310 → 502
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00176
      Location:284 → 638
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:720 → 851
      Helicase_C; Helicase conserved C-terminal domain

    2. XM_005174006.5 → XP_005174063.1  helicase ARIP4 isoform X2

      See identical proteins and their annotated locations for XP_005174063.1

      UniProtKB/TrEMBL
      A0A8N7TAQ7, F1QKJ5, F1R3L6
      Conserved Domains (3) summary
      cd00046
      Location:310 → 502
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00176
      Location:284 → 638
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:720 → 851
      Helicase_C; Helicase conserved C-terminal domain

    3. XM_005174005.5 → XP_005174062.1  helicase ARIP4 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BLB3
      Conserved Domains (3) summary
      cd00046
      Location:328 → 520
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00176
      Location:302 → 656
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:738 → 869
      Helicase_C; Helicase conserved C-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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