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    helq helicase, POLQ like [ Danio rerio (zebrafish) ]

    Gene ID: 562952, updated on 9-Dec-2024

    Summary

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    Official Symbol
    helqprovided by ZNC
    Official Full Name
    helicase, POLQ likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060503-421
    See related
    Ensembl:ENSDARG00000079818 AllianceGenome:ZFIN:ZDB-GENE-060503-421
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    hel308; si:ch211-85e10.2
    Summary
    Predicted to enable several functions, including ATP binding activity; DNA binding activity; and helicase activity. Orthologous to human HELQ (helicase, POLQ like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See helq in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (19330774..19347522)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (19294138..19310886)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene abraxas 1, BRCA1 A complex subunit Neighboring gene mitochondrial ribosomal protein S18C Neighboring gene heparanase Neighboring gene betacellulin, epidermal growth factor family member

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    helicase POLQ-like
    Names
    helicase, mus308-like
    NP_001269352.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001282423.1 → NP_001269352.1  helicase POLQ-like

      Status: PROVISIONAL

      Source sequence(s)
      BX649525
      UniProtKB/TrEMBL
      A0A8M1P553, F1Q4P2
      Related
      ENSDARP00000104305.2, ENSDART00000109412.4
      Conserved Domains (4) summary
      smart00490
      Location:555 → 633
      HELICc; helicase superfamily c-terminal domain
      COG1204
      Location:240 → 960
      BRR2; Replicative superfamily II helicase [Replication, recombination and repair]
      pfam00270
      Location:266 → 427
      DEAD; DEAD/DEAH box helicase
      pfam14520
      Location:930 → 983
      HHH_5; Helix-hairpin-helix domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      19330774..19347522
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395087.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      125379..142127
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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